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      News — inflammation

      CBDA: The Precursor to CBD

      CBDA: The Precursor to CBD

      Where does CBD come from? Most of us know that it comes from a plant, but did you know that CBD actually starts as another compound called CBDA?

      Here at Fully Activated CBD, we want to help you get to the bottom of where CBD comes from by understanding CBDA and the differences between CBD and CBDA. Here’s what we’ll cover:

      • CBD vs. CBDA: what you need to know
      • Why is CBDA less known?
      • What studies have shown about CBDA

      Ready to learn? Read on!

      CBD vs. CBDA: What You Need to Know

      There are three main compounds found in the cannabis plant that can be transformed into cannabinoids: THCA, CBCA, and CBDA. CBDA is the one that develops into CBD.

      CBD has become increasingly well-known in recent years as a potentially important non-psychoactive derivative of the cannabis plant. CBDA is much less common in the retail market, although it’s starting to increase in popularity.

      CBDA turns into CBD in a couple different ways, either by a thermal process (like burning) or by a slower process over time. All the normal ways people consume cannabis naturally turn CBDA into CBD, and it even happens over naturally over time.

      CBD has generated the most interest in terms of medicinal or pharmacological benefits without the psychoactive effects of THC.  In recent years, there has been an upswing of interest in the potential benefits of CBDA, which appear to be different from the benefits of CBD.

      Why Is CBDA Less Known?

      There are a few reasons that CBDA isn’t as well-known as CBD. First, because it degrades into CBD over time, CBDA is considered less stable. In other words, it’s hard to isolate it and turn it into products and supplements.

      Second, CBDA doesn’t affect the body in the same ways as CBD. The human body has receptors called CB1 and CB2 receptors, and cannabinoids like CBD bind to these. While specific results of CBD are still being studied, this receptor mechanism is not disputed.

      CBDA doesn’t work like that, but it seems to affect the body in another way by blocking an enzyme associated with inflammation.

      Because it’s less stable and harder to isolate, CBDA hasn’t generated the same level of interest as CBD, nor has there been as much research into the compound.

      anti-nausea

      What Studies Have Shown About CBDA

      One research study showed that CBDA had structural similarities to common nonsteroidal anti-inflammatory drugs like ibuprofen. It went further to show that the compound showed the same behavior as NSAIDs, as well.

      Another study from 2013 showed a powerful reduction in nausea when CBDA was paired with ondansetron, an anti-nausea drug typically used during chemotherapy.

      Wrapping Up

      Research on CBDA is still ongoing. So while there’s some promise about what CBDA might be able to do, not every possibility of this cannabinoid is yet known. We look forward to learning more about CBDA. In the meantime, Fully Activated CBD is here for you. While we aren’t medical experts, we still want to help you on your CBD journey. Let us know if you have any questions about CBD or CBDA, and we’ll help where we can.

      CBD for the Elderly

      CBD for the Elderly

      The United States is home to one of the largest groups of aging citizens, with researchers suggesting that seniors will outnumber children in this country by the year 2035. With the proposed benefits of CBD changing the way many Americans look at helping themselves with a myriad of ailments, especially older adults, a large group of citizens may be missing out. A Gallup Poll published in 2019 shows that only 8 percent of seniors over the age of 65 personally use a CBD product and as much as 49 percent are not familiar with the cannabinoid at all.

       

      What Is CBD?

      CBD stands for cannabidiol, which is just one of at least 66 cannabinoids in the cannabis family of plants, which includes hemp. CBD has gained a lot of notoriety in the last few years as a potential therapeutic component of cannabis, but CBD was actually known about as far back as 1940. 

      CBD can be found in a lot of different types of products. The cannabinoid is incorporated into an array of tinctures, oils, topical creams, and even edibles. You will find all of these products labeled with things like "full-spectrum" or "CBD isolate." In the most general terms, full-spectrum CBD is created by extracting the CBD and small levels of other cannabinoids from the plant. For example, a full-spectrum product may have trace amounts of THC, terpenes, flavonoids, and other compounds from the plant. On the other hand, a 99 percent pure CBD isolate has been further processed so almost all of the other compounds have been stripped out. Essentially, you will be getting just the CBD. 

       

      Common Issues Seniors Face as They Age 

      CBD has grown to be a popular option for individuals who are looking for a more natural way to potentially help with certain symptoms or ailments. Seniors in particular may benefit from CBD because the cannabinoid may help with ailments seniors often experience. Seniors can be more prone to issues with things like pain and inflammation related to arthritis or illness, digestive issues caused by medications, and certain medical conditions and diseases. While CBD is definitely not a cure-all, it may be a viable option to consider for some issues. 

      The Advantages of CBD 

      While medications can work wonders for symptom management of certain ailments, pharmaceutical drugs can also potentially have undesirable side effects. For example, opioid pain relievers commonly prescribed for pain can cause drowsiness, impaired judgment, constipation, nausea, and risk of overdose. On the other hand, CBD, which may help with pain and inflammation according to some studies, seems to have less undesirable side effects. Therefore, it may be more logical for some seniors to try CBD. Of course, this is not medical advice and you should always consult your doctor before changing anything regarding your medications. 

      Final Thoughts on CBD for the Elderly 

      Always speak to your doctor before trying CBD to discuss any potential medical contraindications. If you are hesitant to try CBD, start out low and slow, monitor for the effects or benefits, and adjust as needed. If you have any questions about CBD, reach out to us at Fully Activated and we'll do our best to answer them. 

       

       

      Sources

      McPhillips, Deidre. “Aging in America, in 5 Charts.” US News, 30 Sept. 2019, www.usnews.com/news/best-states/articles/2019-09-30/aging-in-america-in-5-charts.
      Brenan, Megan. “14% of Americans Say They Use CBD Products.” Gallup, 17 Aug. 2019, news.gallup.com/poll/263147/americans-say-cbd-products.aspx.
      British Journal of Pharmacology. “Cannabinoid Pharmacology: The First 66 Years.” PubMed, 9 Jan. 2006, www.ncbi.nlm.nih.gov/pmc/articles/PMC1760722.
      U.S. National Library of Medicine. “Pain Medications - Narcotics.” MedlinePlus, 4 Aug. 2020, medlineplus.gov/ency/article/007489.htm.
      HHS Public Access. “Cannabinoids as Novel Anti-Inflammatory Drugs.” PubMed, PubMed, 1 Aug. 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614.